Sildenafil Vs Viagra: What’s The Difference And Which One Should You Choose?

When it comes to treating erectile dysfunction (ED), two names often come up: Sildenafil and Viagra. Often, people think they are the same, which they are in some way. However, there are a few factors that differentiate them. Sildenafil is the active ingredient found in Viagra, but there are important distinctions between the two. In this blog post, we will break down the differences, similarities, and factors to consider when choosing between Sildenafil and Viagra for managing ED.

Whether you are looking for a prescription option or trying to understand your treatment choices, this guide will help clarify everything you need to know.

Viagra vs Sildenafil- How Are They Related?

Viagra is the brand name for Sildenafil Citrate and was developed by Pfizer in 1990 for treating erectile dysfunction [1]. Pfizer then patented the drug, allowing the company to sell Viagra without competition for a certain period and recover the money it had spent on research and marketing. This is a key reason why the cost of Viagra is expensive.

Once Pfizer’s patent for Viagra expired, other pharmaceutical companies were allowed to manufacture generic versions of Viagra [2]. Generic medications contain the same active ingredient (Sildenafil Citrate) and work in the same way, but they are significantly more affordable because manufacturers do not need to invest in extensive research and development.

Several pharmaceutical brands now produce generic Sildenafil tablets, such as-

• Cenforce – This is a popular alternative to the brand Viagra, which is manufactured by Centurion Laboratories.
• Malegra- Another generic option is Malegra, which is manufactured by Sunrise Remedies and is known for its effectiveness and affordability.
• Aurogra- Manufactured by Aurochem Laboratories, Aurogra tablets offer a cost-effective yet potent alternative to Viagra.

How Viagra and Sildenafil Are Similar?

Some of the key factors that make Sildenafil and Viagra similar are listed down below.

Active Ingredient

The key similarity between Viagra and Sildenafil is that they contain the same active ingredient- Sildenafil citrate. This chemical works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5) in the body, which helps relax the blood vessels in the penis and facilitates increased blood flow.

Mechanism of Action

Both medications function in the same way by blocking PDE5, which is responsible for the breakdown of cyclic guanosine monophosphate (cGMP), a compound that promotes smooth muscle relaxation and dilation of blood vessels. By increasing the availability of cGMP, Sildenafil and Viagra helps enhance erectile function.

Efficacy

Both medications are taken orally, usually about 30 minutes to an hour before sexual activity, and their effects can last for up to 4 hours [3].

Side Effects and Safety Profile

The side effects of sildenafil and Viagra are identical, including headaches, flushing, nasal congestion, priapism, low blood pressure, back pain, and upset stomach [4]. Rare but serious side effects like sudden vision loss or hearing loss can occur, although these are very uncommon.

Both medications should not be taken with nitrates (commonly prescribed for chest pain) due to the risk of a drop in blood pressure.

Is There A Difference Between Sildenafil And Sildenafil Citrate?

The main difference between Viagra and Sildenafil is its affordability. Additionally, they also differ in their dosage strength, formulation, and availability.

Affordability

Sildenafil is typically more affordable than Viagra, as generics do not carry the same marketing and development costs [5]. Other affordable brand drugs of Sildenafil include Malegra, Aurogra, and Cenforce.

Sildenafil Vs Viagra Dosage

Viagra is available in three dosage strengths, which are 25mg, 50mg, and 100mg. Beginners are advised to start with a lower dose, such as 50mg. On the other hand, Sildenafil is available in dosage strengths of 20mg, 25mg, 50mg, 100mg, and 200mg.

The higher dose of the generic version, such as Malegra 200mg, is commonly recommended for treating severe erectile dysfunction symptoms.

Formulation

While both come in oral tablet form, there may be slight variations in inactive ingredients between the brand and generic versions. However, these do not affect the efficacy or safety of the drug.

Availability

Sildenafil is available under multiple brand names, such as Revatio for pulmonary hypertension, whereas Viagra is marketed exclusively for erectile dysfunction [6].

Sildenafil Versus Viagra- Which One Should You Choose?

When deciding between Sildenafil and Viagra, the primary consideration often comes down to cost, convenience, and personal preference, as both medications work in the same way.

Sildenafil is available as a generic, making it a more affordable option for many patients, while Viagra may be a preferred choice for those who trust the brand or have used it successfully in the past.

Ultimately, the choice between Sildenafil and Viagra should be guided by both your budget and any past experiences with the medication. It is always best to discuss these options with your doctor, who can help you decide the right treatment option for you.

Is Generic Sildenafil Safe And Effective?

Yes, generic Sildenafil is both safe and effective for treating erectile dysfunction, as it contains the same active ingredient as the branded version, Viagra. Generic sildenafil works by increasing blood flow to the penis, helping men achieve and maintain an erection when sexually aroused.

Generic Sildenafil is approved by regulatory authorities such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) [7]. This ensures that it meets rigorous standards for quality, safety, and effectiveness. It undergoes the same testing as the brand-name drug to confirm that it performs in the same way.

How To Take Sildenafil Or Viagra?

When taking Sildenafil or Viagra, it is important to follow the dosage instructions provided by your doctor. Here is a general guide on how to take these medications.

• Take 30 to 60 minutes before sexual activity.
• Best taken on an empty stomach or after a light meal. Always avoid fatty foods as they can delay the effectiveness of the medication.
• Swallow the tablet whole with a glass of water. Do not chew or crush the medication.
• Avoid taking Sildenafil or any of its brand drugs with alcohol to ensure maximum effectiveness.
• Do not take other medication or supplements with Sildenafil without consulting with a doctor.

Are There Other Options?

There are other ED medication options apart from Sildenafil; they are Tadalafil and Vardenafil.

Tadalafil For ED

Tadalafil is known for its prolonged duration of action, with effects lasting up to 36 hours. This earned it the nickname “The Weekend Pill,” as it offers flexibility for spontaneous sexual activity. In addition to ED, Tadalafil is also FDA-approved for the treatment of benign prostatic hyperplasia (BPH), a condition that causes urinary symptoms in men.

Vardenafil For ED

Clinical studies have shown vardenafil to be effective in men with varying degrees of erectile dysfunction, making it suitable for most patients.

Is Viagra Better Than Sildenafil- Our Final Thought

Viagra and sildenafil are the same drug, containing the active ingredient sildenafil citrate, and work in the same way to treat erectile dysfunction. The primary differences between the two are brand/generic medication, cost, and personal preference rather than efficacy or safety.

• Effectiveness– Both Viagra and generic Sildenafil work equally well in treating ED. They have the same active ingredient, so there is no significant difference in how they perform.
• Cost– Generic Sildenafil is much more affordable than Viagra. If cost is a consideration, Sildenafil or generic Viagra is a more budget-friendly choice.
• Trust in the Brand– Some patients may prefer Viagra for its brand recognition and reputation, especially if they have had a positive experience with it.

Both options are equally effective and safe when used as prescribed. If you are looking to save on cost while still getting the same benefits, Sildenafil is a great option. However, if you feel more comfortable with Viagra, that is effective, too. Ultimately, the decision should be based on what fits your needs and works best for your lifestyle.